Nobel Prize in Physiology or Medicine 2025

On Monday, 6 October 2025, the Nobel Assembly at Karolinska Institutet awarded the 2025 Nobel Prize in Physiology or Medicine jointly to Mary E. Brunkow, Frederick J. Ramsdell, and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”

From the press release of Karolinska Institutet:

“The body’s powerful immune system must be regulated, or it may attack our own organs. Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi are awarded the Nobel Prize in Physiology or Medicine 2025 for their groundbreaking discoveries concerning peripheral immune tolerance that prevents the immune system from harming the body.”

Read more about the 2025 Nobel Prize in Physiology or Medicine.